Keywords: Toxicity; Diabetes; Hypertension; Rat.
Abstract-Peptic ulcer is a chronic disease affecting up to 10% of the world’s population & also Liver disease accounts for approximately 2 million deaths per year worldwide. Drug induced gastro-liver toxicities are most common problems all over the world.The purpose of the current experiment was to evaluate the efficacy of anti- diabetic and anti-hypertensive multi-drug therapy in experimental animals while considering the rationale for utilizing PPI and potential herbal therapies.